The Centre is home to several research projects, four of which are funded by the Arts and Humanities Research Council (AHRC).

• Catalogue of English Literary Manuscripts 1450-1700 (CELM)
• Digital Catalogue of Illuminated Manuscripts (DigCIM)
• The Complete Works of John Ford
• Reading Experience Database (RED) Project
• The History of Oxford University Press
• The T. S. Eliot Editorial Project

The Centre also hosts the AHRC National Research Training Scheme (NRTS) in English Language and Literature, Palaeography and the History of the Book.

Other research projects include:

• Early Paper
• Philo-Bibliographical Notes and Queries
• The History of Oxford University Press
• John Masefield Virtual Research Environment
• The William Sharp "Fiona Macleod" Archive